San Francisco 49ers vs. Detroit Lions (9/12/21) - NFL Week 1
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49ers 41-33 Lions (Sep 12, 2021) Final Score - ESPN
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San Francisco 49ers vs. Detroit Lions Game Images (Week 1)
NFL 2021 - WEEK 1 Schedule
San Francisco 49ers vs. Detroit Lions Game Images (Week 1)
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Key stats from the 49ers' 41-33 Week 1 win over the Lions
Key stats from the 49ers' 41-33 Week 1 win over the Lions
Trey Lance throws first NFL TD pass
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Recap: Detroit Lions late comeback falls short in season opener, fall to 49ers, 41-33 - Pride Of Detroit
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